Globally distinguishing PC features included CCR10, TNFRSF17 (BCMA), SDC1 (CD138), MZB1, DERL3, PRDX4, XBP1, CD63, CD160, CD59, ICAM2 and CALR, as well as insulin‐like growth factor 1 (IGF1; Supplementary table 14). The gene discussed is CD63; the disease is pachyonychia congenita.