Follow-up: This patient was given multiple hormone replacement including: (1) glucocorticoid replacement: 10 mg hydrocortisone p.o. in the morning and 5 mg p.o. in the afternoon, and was suggested to increase the glucocorticoid dose by 3–5 times when under stress; (2) thyroid hormone supplementation: levothyroxine 75 μg p.o. in the morning; (3) insulin therapy of T1DM: insulin glargine 7 U subcutaneously before bedtime, insulin aspart 4 U before three meals, and the patient was taught and trained to titrate insulin dosage according to blood sugar levels. This evidence concerns the gene TG and type 1 diabetes mellitus.