ACOX2 and posterior cortical atrophy: In addition to proliferation, the wound healing assay showed that overexpression of ACOX2 hindered PCa cell migration (Figure 8D and Figure s2C, for PC-3: P < 0.05, for 22Rv1: P < 0.05) and the reduced invasiveness of ACOX2 overexpressing PCa cell lines was measured by transwell assay (Figure 8E and Figure s2D, for PC-3: P < 0.01, for 22Rv1: P < 0.01).