ACOX2 and posterior cortical atrophy: Overexpression of ACOX2 inhibited PCa cell viability as detected by CCK-8 assay (Figure 8B, for PC-3: P < 0.01, for 22Rv1: P < 0.01), and a similar result was observed in the colony formation assay: overexpressing ACOX2 attenuated PCa cell proliferation (Figure 8C and Figure s2B, for PC-3: P < 0.01, for 22Rv1: P < 0.01).