TRPV3 and breast carcinoma: From fluorescence intensity taken by laser scanning confocal microscope, we found that Carvacrol treatment significantly increased [Ca2+]i, and decreased [Ca2+]i through TRPV3 siRNA in breast cancer cells (Fig. 5A), which suggesting that the effect of TRPV3 in MCF-7 cells is significantly associated with [Ca2+]i.