Our analysis revealed that TIE1 is downregulated compared to normal tissues in bladder carcinoma (BLCA), breast cancer (BRCA), kidney chromophobe (KICH), kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC) and uterine corpus endometrial carcinoma (UCEC). The gene discussed is TIE1; the disease is urinary bladder carcinoma.