Conversely, higher levels of TIE1 were observed in cholangiocarcinoma (CHOL), head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), liver hepatocellular carcinoma (LIHC) and stomach adenocarcinoma (STAD) compared to normal tissues (Figure 1A). This evidence concerns the gene TIE1 and gastric adenocarcinoma.