Li et al. [85] reported that an amide anthraquinone derivative named 1-nitro-2-acyl anthraquinone glycine (C10) had a high binding affinity to JAK2, leading to downregulation of the JAK2/STAT3 signaling pathway, resulting in the induced cell cycle arrest and inhibiting cell proliferation in HCT116 and HT29 colon cancer cells. This evidence concerns the gene STAT3 and malignant colon neoplasm.