We further investigated the relation between GRHL2 and CD73 protein expression levels by IHC on samples of human breast cancer tissue, choosing a set of 10 GRHL2-high, 10 GRHL2-low (based on RNA-seq), and 10 metaplastic breast adenocarcinoma patient tumors as these were expected to be heterogeneous. Here, GRHL2 is linked to breast carcinoma.