This is of interest considering that mice with hepatocyte-specific deletion of Lrpprc as well as LSFC patients present with major lipid changes evocative of NAFLD, including increased triglyceride and long-chain acylcarnitine levels and altered phospholipid content (Ruiz et al., 2019). The gene discussed is LRPPRC; the disease is metabolic dysfunction-associated steatotic liver disease.