Significant overexpression of m6A regulators IGFBP3, IGFBP5, and ALKBH6 characterizes IPF patients, with a positive association between elevated METTL16 levels and ALKBH6, highlighting the pivotal role of m6A modification regulators as IPF biomarkers.173. This evidence concerns the gene ALKBH6 and idiopathic pulmonary fibrosis.