For molecular imaging, tumor models with different levels of FAP expression were developed using the following cell lines: BxPC-3 (human pancreatic cancer), Panc-02 (murine pancreatic cancer), HT-1080 (human fibrosarcoma), and HT1080-FAP (HT1080 with stable overexpression of human FAP). Here, FAP is linked to familial pancreatic carcinoma.