CD28 and gestational diabetes: Concretely, the odds ratio (OR) of CD127 on CD28+ CD45RA+ CD8br on GDM risk was estimated to be approximately 0.919 (95% CI: 0.860–0.982, P = 0.0125, PFDR = 0.040) by the IVW method, whereas the MR Egger (95% CI: 0.830–1.071, OR = 0.943, P = 0.375) and weighted median (95% CI: 0.827–0.998, OR = 0.909, P = 0.045) analyses were consistent with the IVW.