SPINK1 and head and neck squamous cell carcinoma: The highest ranked transcript was SPINK1 which was consistently downregulated in all cases with decreasing expression from low-grade (-1.03-fold, p = 0.616) to moderate (-1.16-fold, p = 0.109) to high-grade dysplasia (-1.39-fold, p < 0.005), and lowest expression in HNSCC (-1.71-fold, p < 10-4).