Other differentially expressed transcripts include S100A7, LCN2, CXCL14, and CD207 (decreasing expression from premalignant lesions to invasive carcinoma), as well as IDO1, IL6, IL8, THBS1, and FN1 (increasing expression from premalignant lesions to invasive carcinoma). The gene discussed is THBS1; the disease is invasive carcinoma.