In nasopharyngeal carcinoma, early tumor metastasis is linked with the EBV LMP1-mediated increase in the expression of Vimentin73, and high Vimentin expression is often significantly associated with the advanced clinical stage and lymph node metastasis in nasopharyngeal carcinoma tissues74. This evidence concerns the gene PDLIM7 and metastatic malignant neoplasm in the lymph nodes.