In addition to these transcriptional mechanisms, our research found that in sepsis, Pfkfb3 upregulation in monocytes and macrophages is also posttranscriptionally regulated by miR-106a-5p, with a decrease in miR-106a-5p during sepsis leading to the stabilization of Pfkfb3 mRNA. This evidence concerns the gene PFKFB3 and Sepsis.