Bie et al. [74] indicated that yes-associated protein (YAP) could inhibit L-PTGDS and PTGDR2, which promotes stemness in gastric cancer stem cells (GCSCs), whereas PTGDR2 or L-PTGDS overexpression can block the YAP-induced self-renewal of GCSC. The gene discussed is PTGDR2; the disease is gastric cancer.