report that VEGF‐C can improve the efficacy of immune checkpoint blockade by enhancing the priming of anti‐tumor CD8+ T cell responses in the draining dCLNs, thus promoting immune surveillance and eradication of tumors.[33] Similarly, VEGF‐C overexpression improved the efficacy of radiotherapy in the treatment of brain tumors.[34] Together, previous studies have laid the foundation for a new therapeutic strategy to alleviate neuroinflammation and enhance immunosurveillance by VEGF‐C stimulation. Here, CD8A is linked to brain neoplasm.