TGFB1 and neoplasm: Considering the multifaceted effects of IR‐LND@Lip, including enhanced cytotoxicity of T cells, downregulation of PD‐L1/TGF‐β dual immune proteins, and reversal of the fibrotic tumor microenvironment in vitro, we hypothesized that it can proficiently alleviate T‐cell exhaustion, consequently enhancing the efficacy of radio‐immunotherapy in vivo.