The relative CRC-EVArray readouts pertaining to the distinct subgroups of serum-derived EVs from AA patients in the train set were summarized in Fig. 6B. Strikingly, our observation revealed a conspicuous upsurge in the levels of EVs surface proteins, FIBG, PDGF-β, and TGF-β, within AA patients (Fig. 6C, E). The gene discussed is TGFB1; the disease is colorectal carcinoma.