In addition, despite the involvement of prostaglandins in pathogenic Th17 cell-driven inflammation including psoriasis [46], impaired autophagy did not affect the expression levels of Pgts2, encoding COX-2; mPges-1 (a prostaglandin E2 synthase); and Hpgds (a prostaglandin D2 synthase) in myeloid cells (Supple. This evidence concerns the gene HPGDS and psoriasis.