Psoriasis is an inflammatory skin disease characterized by hyperproliferative epidermal keratinocytes (KC) and excessive infiltration of immune cells, including lymphocytes, neutrophils, and macrophages, into the inflamed skin lesion, leading to the production of various cytokines, such as TNF-α, IL-23, and IL-17 [1–4]. This evidence concerns the gene TNF and inflammatory skin disease.