MAPT and Alzheimer disease: Unlike the Aβ and tau PET SUVRs data, which showed extended statistically significant differences across all brain regions for CU and AD participants (ANCOVA post-hoc t-tests with age and sex as covariates, p < 0.05), microglial activation images exhibited differences in only 30 regions (i.e., approx. 45%; Supplementary Table 5).