In addition, reverse MR showed significant negative instrumental effects of FEV1 (−15.20 mg/L; 95%CI: −24.29, −1.51; P = 1.05 × 10−03) and FVC (−17.48 mg/L; 95%CI: −29.08, −1.74; P = 3.16 × 10−03) on hsCRP, whereas we only observed significant negative instrumental effects of per doubling odds of asthma (−16.12 mg/L; 95%CI: −22.94, −9.31; P = 3.53 × 10−06) on albumin. The gene discussed is ALB; the disease is asthma.