Nurr1 overexpression in the primary motor cortex did not affect activation of Iba1-positive microglia/macrophages in the peri-hematoma region (Fig. 3e), accumulation of GFAP-positive astrocytes in the peri-hematoma region (Fig. 3f), increases in nitrotyrosine immunoreactivity reflecting nitric oxide-mediated nitrosative/oxidative stress (Fig. 3g) and the survival of NeuN-positive neurons in the central region of hematoma (Fig. 3h). Here, AIF1 is linked to hematoma.