Lambda interferons (IFNLs) include IFNL1/interleukin-29 (IL-29), IFNL2/IL‐28A, IFNL3/IL‐28B, and IFNL4, all of which are critical for a balanced antiviral response in the respiratory tract for optimal protection against infection and minimizing associated damage [8]. Here, IFNL1 is linked to infection.