IFNG and cancer: Interestingly γδ T cells are found to be necessary for immunosuppressive macrophage polarization during non‐cancerous experimental model of lung inflammation,102 while in cancer microenvironment MDSCs, mesenchymal cells, immunosuppressive TAMs and Tregs cumulatively prevent the infiltration and cytotoxic activity of γδT cells by inhibiting their secretion of IFN‐γ and promoting synthesis and release of immunosuppressive molecules.103, 104, 105