CRP and Erythema: The Centers for Disease Control and Prevention (CDC) case definition of MIS-C developed a new case definition for MIS-C diagnostic criteria, including: persistent fever > 38 ° C, in the absence of an alternative diagnosis and the exclusion of other microbiological causes, in a clinically severe patient; C-reactive protein (CRP) > 3 mg/dl; > 2 new-onset manifestations of the following: rash, conjunctivitis, oral mucosal changes, erythema and/or oedema of the extremities; vomiting, diarrhoea, abdominal pain; lymphocyte count < 1000/ μl, platelet count < 150,000/μl.