By importing results into Cytoscape and employing the cytohubba plugin’s MCC algorithm, 10 mitochondrial genes closely related to sepsis were identified, including NDUFA2, COX7C, UQCRH, UQCR11, NDUFB6, COX7B, NDUFA1, NDUFA4, COX7A2, and NDUFB3 (Fig. 4B). This evidence concerns the gene COXFA4 and Sepsis.