Consequently, we aimed to evaluate and compare the predictive capabilities of urinary biomarkers [TIMP-2]•[IGFBP7] and CCL14 for renal non-recovery, the initiation of KRT in the ICU, and 30-day mortality, focusing specifically on a relatively homogeneous population of patients with SA-AKI. The gene discussed is IGFBP7; the disease is acute kidney injury.