The logistic regression model to predict RPQ at 2-weeks had an R2 = 0.32 and included obese BMI (p = 0.01), severely obese BMI (p = 0.01), the interaction of severely obese BMI and ASC (conditional effect: 29.0, p < 0.001), interaction of obese BMI with caspase-1 (conditional effect: 18.8, p < 0.001), interaction of severely obese BMI and IL-18 (p = 0.01), and diabetes (p = 0.04) as significant predictors. The gene discussed is IL18; the disease is diabetes mellitus.