The model to predict SF-12 physical at 6-months had an R2 = 0.31 and included IL-1β as a significant predictor (p = 0.00), IL-18 (p = 0.05), the interaction of obese BMI and IL-1β (p = 0.04), and diabetes (p = 0.02), and reporting comorbid diabetes worsened SF-12 physical score at 6-months. The gene discussed is IL1B; the disease is diabetes mellitus.