KCNK16 and Glucose intolerance: Although greater β-cell Kcnk16 expression could also be responsible for the more significant impairment in glucose intolerance observed in Kcnk16 L114P male mice, there is only a trend for greater Kcnk16 expression in sorted male β-cells (average RPKM 6296.25±953.84) compared to sorted female β-cells (5148.25±1013.22); this is similar in β-cells from high-fat diet (HFD)-treated mice (average RPKM 8020.75±1944.41 for males, and average RPKM 7551±2952.70 for females) (Brownrigg et al., 2023).