To date, the following six CAR-T gene therapies have been approved only in the field of incurable blood cancer, including CD19 and B-cell maturation antigen (BCMA) targets (Mazinani & Rahbarizadeh, 2022): KymriahTM (B-cell acute lymphoblastic leukemia [ALL] and B-cell non-Hodgkin lymphoma [NHL]), YescartaTM (NHL and follicular lymphoma), TecartusTM (Mantle cell lymphoma and ALL), BreyanzyTM (NHL), AbecmaTM (multiple myeloma), and CarvykteTM (multiple myeloma). This evidence concerns the gene TNFRSF17 and hematopoietic and lymphoid system neoplasm.