LGI1 and Anxiety: FBDS can also be mistaken for myoclonus and therefore interpreted as suggesting a diagnosis of Creutzfeldt–Jakob Disease (CJD).12,13 Depression/anxiety, paranoia, hallucinations and anxiety occur in at least 50% of people with LGI1-Ab-E8 and, conversely, temporal lobe seizures can mimic panic or anxiety attacks.1