The albumin (p = 0.003), Hb (p = 0.003), PT (p = 0.006), INR (p = 0.007), Child-Pugh score (p < 0.001), MELD score (p = 0.008), ascites (p = 0.005), sarcopenia (p < 0.001) and NSBBs (p = 0.018) were the potential factors that predicted 2-year rebleeding in univariable regression analysis. This evidence concerns the gene ALB and sarcopenia.