The levels of CEA, CA153 and CA125 innipple discharge with the tumor diameter 5cm, highclinical stage, low differentiation and recurrence weresignificantly higher than those in nipple dischargewith the tumor diameter 5 cm, low clinical stage,high differentiation and no recurrence and metastasis,and the prognosis could be evaluated accordingto their expression levels. Here, CEACAM5 is linked to neoplasm.