Another reason for increased AMH may beinsulin, and Glueck et al. [10] observed a direct correlationbetween AMH and insulin insensitivity.Obesity can cause an increase in ovarian hyperandrogenproduction by a combination of follicular membranecell stimulation and ovarian function upregulation.Additionally, obesity has been shown to increaseinsulin resistance and compensatory hyperinsulinemia,which further promotes adipogenesis whileinhibiting lipolysis. The gene discussed is INS; the disease is hyperinsulinism.