SV2A and Alzheimer disease: Conversely, the second small study (10 AD (5 at aMCI and 5 at mild dementioa stages) and 10 controls) using 11C-UCB-J PET and 18F-flortaucipir (tau) PET suggested a possible inverse correlation between both tracers, including a stronger inverse correlation between tau deposits in the entorhinal cortex and SV2A density in the hippocampus (Mecca et al., 2022a).