COPS3 and COVID-19: The results from the ROC curve analysis showed that DHX15, USP14, COPS3, TYK2, and RIOK had AUC values of 0.931, 0.917, 0.986, 0.903, and 0.917, respectively, for T2DM (Figure 5A) and AUC values of 0.960, 0.860, 1.0, 0.9, and 0.90, respectively, for COVID-19 (Figure 5B).