Based on GSE4588 dataset, CD39 was decreased and ADA1 was increased in B cells from SLE, while based on GSE10325 dataset for B cells, there were no significant difference of the expression of CD39, CD73, ADA1 and ADA2 between SLE and healthy controls (Fig. 2C and D). Here, ADA2 is linked to systemic lupus erythematosus.