In the tumor, IFNγ stimulates the production of CXCL9 by tumor and stromal cells, resulting in increased infiltration of CXCR3+ (CXCL9 receptor) cytotoxic immune cells (such as CD8+ T cells and Natural Killer cells) into the tumor that promotes its eradication (Figure 1B). The gene discussed is CXCL9; the disease is neoplasm.