NFKB1 and colitis: In addition, one study also found that fermented wild ginseng could relieve the symptoms of colitis in a DSS-induced colitis animal model through inhabiting secretion level of proinflammatory cytokines (IL-1β, IL-6, IL-12, p40, TNF-α, and IFN-γ) and blocking NF-κB signaling pathway (82).