MIP-1A is produced by a variety of cell types, including monocytes, fibroblasts, vascular endothelial cells, and smooth muscle cells (59), has chemotactic effects on monocytes, T cells, B cells (60, 61), and is involved in the pathogenesis of several inflammatory diseases such as RA and asthma (62–64). This evidence concerns the gene CCL3 and asthma.