Through in vivo and in vitro experiments, Ma et al. found that miRNA-93 significantly reduced LATS2 expression and YAP phosphorylation in the myocardium after myocardial infarction by targeting LATS2, which inactivated the Hippo/YAP pathway, increased YAP nuclear activity and transcriptional activity, inhibited myocardial fibrosis, and promoted cardiomyocyte viability, thereby improving cardiac function preservation after myocardial infarction. Here, YAP1 is linked to myocardial infarction.