In addition, the expression of circular RNA cerebellar degeneration-related protein 1 antisense (Circ-CDR1as) is also upregulated in diabetic cardiomyopathy, which activates the Hippo pathway involved in the function of Alk B homolog 5 (ALKBH5), an m6A demethylation enzyme, and FOXO3 by significantly inhibiting mammalian sterile 20-like kinase 1 (MST1) ubiquitination degradation, thereby mediating cardiomyocyte apoptosis. This evidence concerns the gene MST1 and diabetic cardiomyopathy.