Through in vivo and in vitro experiments, Ma et al. found that miRNA-93 significantly reduced LATS2 expression and YAP phosphorylation in the myocardium after myocardial infarction by targeting LATS2, which inactivated the Hippo/YAP pathway, increased YAP nuclear activity and transcriptional activity, inhibited myocardial fibrosis, and promoted cardiomyocyte viability, thereby improving cardiac function preservation after myocardial infarction. The gene discussed is LATS2; the disease is myocardial infarction.