YAP1 and cardiac hypertrophy: lncExACT1-DCHS2 increases the content of p-YAP, inhibits the nuclear and transcriptional activity of YAP1, inhibits the role of YAP1 in exercise-induced cardiac growth and myocardial production, and plays a role in promoting pathological myocardial hypertrophy and fibrosis, thereby promoting the development of cardiac dysfunction (Li et al., 2022a).