ERBB2 and breast carcinoma: Here, we describe the findings of three independent and extemporaneous experiments consistent with that conducted by (1): the reproducibility of lung adenocarcinomas following the administration of CFFs derived from mammary ductal carcinomas (2), the induction of pre-neoplastic changes and truthful malignancies resulting from the administration of pancreatic adenocarcinoma and metastatic melanoma in otherwise normal nude mice, and (3) that zebrafish embryos exposed to breast carcinoma CFFs diluted in aquarium water broadly expressed HER-2 and overexpressed the C-Myc oncogene.