Similar results was observed that silencing of GTSE1 represses cell proliferation, mobility and invasion have been reported in non-small-cell lung cancer cells [21], clear cell renal cell carcinoma [19, 20], esophageal squamous cell carcinoma [27], colon cancer [32], bladder cancer [14], acral melanoma [15], and hepatocellular carcinoma [17]. This evidence concerns the gene GTSE1 and hepatocellular carcinoma.