Two siRNAs targeting GTSE1 (si-GTSE1#1 and si-GTSE1#2) were transfected into C666-1 and SUNE-1 cells to downregulate the level of GTSE1 in order to investigate the role of GTSE1 in the progression of NPC. This evidence concerns the gene GTSE1 and nasopharyngeal carcinoma.