IL1B and alkaline phosphatase measurement: Research on AP has shown that AP is caused by the premature activation of the pancreas through the release of large amounts of digestive enzymes from acinar cells, causing autodigestion of the pancreas and subsequent release of inflammatory cytokines and chemokines such as interleukin (IL)-1β, IL-6, tumour necrosis factor (TNF)-α and nitric oxide (NO) [4].