The KEGG pathway enrichment analysis results showed that wogonin in the treatment of AML-M5 mainly focused on the PI3K-Akt signaling pathway, lipid, and atherosclerosis, human cytomegalovirus infection, Kaposi's sarcoma-related herpesvirus infection, and hepatitis B (Fig. 4B). This evidence concerns the gene AKT1 and hepatitis A virus infection.