HLA-A and colorectal carcinoma: Even though the difference between normal and CRC tissue was not statistically significant, we note that there is a definite trend toward decreased CRC expression levels compared with normal tissue, with Z-scores of − 1.30 (P = 0.19), − 1.06 (P = 0.28), and − 1.75 (P = 0.07) for HLA-A, B, and C alleles, respectively.