Through the published studies, we confirmed the promotion (LDHA [39], PGAM4 [40], ACSS2 [41], PGAM1 [42, 43], ENO2 [44], ALDOA [45], BPGM [46], PFKL [47], HK1 [48], PGM2 [49], ALDOC [50], PGK1 [51], PFKP [52], TPI1 [53, 54], and ALDH3B1 [55]) or inhibition (ALDH2 [56], PCK2 [57], and FBP2 [58, 59]) functions of these genes on glycolysis, and the result confirmed that NREP affects glycolysis of BC cells. The gene discussed is HK1; the disease is breast cancer.