Z2-LO10 is a modular biologic drug for cancer treatment that consists of a dimeric affibody targeting domain and a potent bacterial toxin payload18,48–50; TEV protease is commonly used to cleave recombinant proteins from their tags51; and TdT is a reagent for the TUNEL apoptosis assay and for the de novo synthesis of DNA17,52,53. Here, DNTT is linked to cancer.