This was also accompanied by an increased expression of programmed cell death-1 ligand 1 (PD-L1, CD274) in both SLGN-treated and LPS-treated KCs (online supplemental figure S2B, figure 2B), which is in line with previous observations in SLGN-treated polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSCs).11 Here, CD274 is linked to dry eye syndrome.