NFE2L2 and colorectal carcinoma: Among other transcription factors (Supplementary Table S6), we found high correlation for NFE2L2(r = 0.39,P = 1.742e-28), which regulates stress response (Sanchez-Vega et al. 2018) andhas been recently found involved in CRC resistance to therapy (O’Cathail et al. 2021).